Prothrombin lub sij hawm (PT) yog hais txog lub sij hawm xav tau rau plasma coagulation tom qab hloov pauv ntawm prothrombin mus rau thrombin tom qab ntxiv cov ntaub so ntswg thromboplastin ntau dhau thiab qhov tsim nyog ntawm calcium ions rau platelet-plasma tsis txaus.Lub sij hawm prothrombin siab (PT), uas yog, lub sij hawm ncua sij hawm, tej zaum yuav tshwm sim los ntawm ntau yam xws li congenital txawv txav coagulation yam, tau txais txawv txav coagulation yam, txawv txav ntshav anticoagulation xwm txheej, thiab lwm yam. Lub ntsiab tsom xam yog raws li nram no:
1. Cov yam ntxwv ntawm congenital coagulation: Kev tsim tawm txawv txav ntawm ib qho ntawm coagulation yam I, II, V, VII, thiab X hauv lub cev yuav ua rau lub sij hawm prothrombin ntev (PT).Cov neeg mob muaj peev xwm ntxiv coagulation yam nyob rau hauv cov kev taw qhia ntawm kws kho mob los txhim kho qhov teeb meem no;
2. Qhov txawv txav tau txais coagulation yam: kab mob siab heev, vitamin K deficiency, hyperfibrinolysis, disseminated intravascular coagulation, thiab lwm yam, cov yam ntxwv no yuav ua rau tsis muaj coagulation yam hauv cov neeg mob, ua rau lub sij hawm ntev prothrombin (PT).Cov laj thawj tshwj xeeb yuav tsum raug txheeb xyuas rau kev kho mob.Piv txwv li, cov neeg mob uas tsis muaj vitamin K tuaj yeem kho nrog cov tshuaj vitamin K1 hauv cov hlab ntsha los txhawb kev rov qab los ntawm lub sijhawm prothrombin mus rau qhov qub;
3. Cov ntshav tsis zoo rau lub xeev anticoagulation: muaj cov tshuaj anticoagulant hauv cov ntshav los yog tus neeg mob siv cov tshuaj anticoagulant, xws li tshuaj aspirin thiab lwm yam tshuaj, uas muaj cov nyhuv anticoagulant, uas yuav cuam tshuam rau coagulation mechanism thiab ncua lub sij hawm prothrombin (PT).Nws raug nquahu kom cov neeg mob tso tseg cov tshuaj anticoagulant raws li kev qhia ntawm kws kho mob thiab hloov mus rau lwm txoj kev kho mob.
Prothrombin lub sij hawm (PT) ncua ntev dua 3 vib nas this muaj qhov tseem ceeb hauv kev kho mob.Yog tias nws tsuas yog siab dhau lawm thiab tsis pub tshaj tus nqi ib txwm siv rau 3 vib nas this, nws tuaj yeem ua tib zoo saib, thiab kev kho tshwj xeeb feem ntau tsis tas yuav tsum tau ua.Yog hais tias lub sij hawm prothrombin (PT) ntev dhau lawm, nws yog ib qho tsim nyog yuav tsum paub ntxiv txog qhov laj thawj tshwj xeeb thiab ua tiav kev kho mob.