01. Ka launa mua me D-dimer, FDP

1. ʻO FDP ka huaʻōlelo maʻamau no nā huahana hoʻohaʻahaʻa like ʻole o ka fibrin a me ka fibrinogen ma lalo o ka hana a ka plasmin, e hōʻike nui ana i ka pae fibrinolytic holoʻokoʻa o ke kino;

2. ʻO D-dimer kahi huahana hoʻohaʻahaʻa kikoʻī o ka fibrin i hoʻopili ʻia ma lalo o ka hana o ka plasmin, a ʻo ka piʻi ʻana o kona pae e hōʻike ana i ke ola o ka hyperfibrinolysis lua;

02. Hoʻohana maʻi o D-dimer a me FDP

Hoʻokaʻawale i ka thrombosis venous (VTE me DVT, PE)

ʻO ka pololei o ka D-dimer maikaʻi ʻole o ka thrombosis vein hohonu (DVT) hiki ke hiki i 98% -100%

Hiki ke hoʻohana ʻia ka ʻike D-dimer e kāpae i ka thrombosis venous

♦Significance i ka hōʻailona o DIC

1. ʻO DIC kahi kaʻina pathophysiological paʻakikī a me ka maʻi thrombo-hemorrhagic maʻi i loaʻa nui.ʻO ka hapa nui o nā DIC he wikiwiki ka hoʻomaka, ka maʻi paʻakikī, ka ulu wikiwiki, ka maʻi paʻakikī, a me ka wānana weliweli.Inā ʻaʻole ʻike koke ʻia a mālama maikaʻi ʻia, Hoʻopilikia pinepine i ke ola o ka mea maʻi;

2. Hiki i ka D-dimer ke hōʻike i ke koʻikoʻi o DIC i kekahiʻano, hiki ke hoʻohanaʻia ka FDP e nānā i ka uluʻana o ka maʻi ma hope o ka hōʻoiaʻana o ka maʻi, a me ka antithrombin (AT) kōkua e hoʻomaopopo i ka paʻakikī o ka maʻi a me ka pono o ka maʻi. lapaʻau heparin ʻO ka hui pū ʻana o D-dimer, FDP a me ka hoʻāʻo AT ua lilo i hōʻailona maikaʻi loa no ka hoʻomaʻamaʻa ʻana i ka DIC.

♦Significance i loko o nā maʻi maʻi maʻi

1. Pili loa nā maʻi ʻino ʻino i ka hana ʻino o ka hemostasis.ʻAʻole pili i nā maʻi maʻi maʻi paʻa a i ʻole leukemia, e loaʻa i nā mea maʻi ke kūlana hypercoagulable koʻikoʻi a i ʻole thrombosis.ʻO Adenocarcinoma paʻakikī e ka thrombosis ka mea maʻamau;

2. He mea pono ke hoʻoikaika i ka thrombosis he hōʻailona mua o ka maʻi maʻi.I nā poʻe maʻi me ka thrombosis vein hohonu i hiki ʻole ke ʻike i nā kumu pilikia o ka thrombosis koko, aia paha kahi maʻi maʻi.

♦Clinical significance o nā maʻi ʻē aʻe

1. Ka nānā 'ana i ka thrombolytic drug therapy

I ka wā o ka mālamaʻana, ināʻaʻole lawa ka nui o ka lāʻau thrombolytic aʻaʻole i hoʻopau loaʻia ka thrombus, e mālamaʻo D-dimer a me FDP i kahi kiʻekiʻe ma hope o ka hikiʻana i ka piko;ʻoiai ka nui o ka lāʻau thrombolytic e hoʻonui i ka pilikia o ke koko.

2. ʻO ke koʻikoʻi o ka mālama ʻana i ka heparin mole liʻiliʻi ma hope o ke ʻoki ʻana

Hoʻomaʻamaʻa pinepine ʻia nā maʻi me ka ʻeha / ʻoki me ka prophylaxis anticoagulant.

ʻO ka maʻamau, ʻo 2850IU/d ka nui o ka nui o ka mole liʻiliʻi heparin, akā inā ʻo ka pae D-dimer o ka mea maʻi he 2ug/ml ma ka lā 4 ma hope o ke ʻoki ʻana, hiki ke hoʻonui ʻia ka nui i 2 mau manawa i ka lā.

3. Acute aortic dissection (AAD)

ʻO ka AAD kahi kumu maʻamau o ka make koke i nā maʻi.Hiki i ka hoʻomaʻamaʻa mua ʻana a me ka mālama ʻana ke hōʻemi i ka nui o ka make o nā maʻi a hōʻemi i nā pilikia olakino.

ʻO ka mea hiki ke hoʻonui i ka D-dimer ma AAD: Ma hope o ka hoʻopōʻino ʻana o ka papa waena o ka pā o ka moku aortic ma muli o nā kumu like ʻole, ua haki ka pā vascular, e hoʻokau i ke koko i loko a me waho e hana i kahi "waha wahaheʻe". , Ma muli o ke koko maoli a me ka wahaheʻe i loko o ka lua He ʻokoʻa nui i ka wikiwiki o ka holo, a ʻo ka wikiwiki o ka holo ʻana i loko o ka lua wahaheʻe he lohi, hiki ke maʻalahi i ka thrombosis, hoʻoulu i ka ʻōnaehana fibrinolytic, a hoʻoikaika i ka hopena. ka piʻi ʻana o ka pae D-dimer.

03. Nā mea e pili ana i ka D-dimer a me ka FDP

1. Nā hiʻohiʻona kino

Hoʻokiʻekiʻe: Aia nā ʻokoʻa nui i ka makahiki, nā wahine hāpai, ka hoʻoikaika ikaika, ka menstruation.

2. Ka hopena o ka maʻi

Hoʻokiʻekiʻe: cerebrovascular stroke, thrombolytic therapy, maʻi nui, sepsis, tissue gangrene, preeclampsia, hypothyroidism, maʻi ate koʻikoʻi, sarcoidosis.

3.Hyperlipidemia a me nā hopena o ka inu ʻana

Hoʻokiʻekiʻe: nā mea inu;

Hoemi: hyperlipidemia.

4. Nā hopena lāʻau

Hoʻokiʻekiʻe: heparin, nā lāʻau antihypertensive, urokinase, streptokinase a me staphylokinase;

Hoʻoemi: nā mea hōʻemi waha a me ka estrogen.
04. Hōʻuluʻulu manaʻo

ʻO ka ʻike D-dimer a me ka FDP he palekana, maʻalahi, wikiwiki, waiwai, a paʻakikī loa.E loaʻa iā lāua ʻelua nā pae like ʻole o ka hoʻololi ʻana i ka maʻi cardiovascular, ka maʻi ate, ka maʻi cerebrovascular, ke kiʻekiʻe o ka hāpai ʻana, a me ka pre-eclampsia.He mea nui e hoʻoholo i ke koʻikoʻi o ka maʻi, nānā i ka hoʻomohala ʻana a me ka hoʻololi ʻana o ka maʻi, a me ka loiloi i ka prognosis o ka hopena curative.hopena.