ʻO ka manawa Thrombin (TT) a me ka manawa prothrombin (PT) ka mea maʻamau i hoʻohana i nā hōʻailona ʻike coagulation, ʻo ka ʻokoʻa ma waena o nā mea ʻelua aia i ka ʻike ʻana i nā kumu coagulation like ʻole.

ʻO ka manawa Thrombin (TT) kahi hōʻailona o ka manawa e pono ai e ʻike i ka hoʻololi ʻana o ka prothrombin plasma i thrombin.Hoʻohana nui ʻia ia e loiloi i ke kūlana hana o fibrinogen a me nā mea coagulation I, II, V, VIII, X a me XIII i ka plasma.I ka wā o ka ʻike ʻana, ua hoʻohui ʻia kahi nui o ka prothrombin a me nā ion calcium e hoʻohuli i ka prothrombin i ka plasma i thrombin, a ua ana ʻia ka manawa hoʻololi, ʻo ia ka waiwai TT.

ʻO ka manawa Prothrombin (PT) kahi helu helu e ʻike ai i ka hana o nā mea hoʻohui koko ma waho o ka ʻōnaehana coagulation koko.I ka wā o ka ʻike ʻana, ua hoʻohui ʻia kekahi nui o ka coagulation factor composition (e like me nā coagulation factor II, V, VII, X a me fibrinogen) e hoʻāla ai i ka ʻōnaehana coagulation, a ua ana ʻia ka manawa no ka hoʻokumu ʻana i ka clot, ʻo ia ka waiwai PT.Hōʻike ka waiwai PT i ke kūlana o ka hana coagulation ma waho o ka ʻōnaehana coagulation.

Pono e hoʻomaopopo ʻia ʻo nā helu TT a me PT ka mea maʻamau i hoʻohana ʻia i nā hōʻailona e ana i ka hana coagulation, akā ʻaʻole hiki i nā mea ʻelua ke pani i kekahi i kekahi, a pono e koho ʻia nā hōʻailona ʻike kūpono e like me ke kūlana kikoʻī.I ka manawa like, pono e hoʻomaopopo ʻia e pili ana nā ʻokoʻa i nā ʻano ʻike a me nā reagents i ka pololei o nā hopena, a pono e uku ʻia ka nānā ʻana i nā hana maʻamau i ka hana lapaʻau.