ʻO ka thrombosis a me ka hemostasis nā hana physiological koʻikoʻi o ke kino o ke kanaka, e pili ana i nā kīʻaha koko, platelets, coagulation factor, anticoagulant proteins, a me nā ʻōnaehana fibrinolytic.He hoʻonohonoho lākou o nā ʻōnaehana kaulike kūpono e hōʻoia i ke kahe maʻamau o ke koko i loko o ke kino kanaka.Ka holo mau ʻana o ke kahe, ʻaʻole kahe i waho o ke kīʻaha koko (hemorrhage) a ʻaʻole hoʻi ka coagulation i loko o ke kīʻaha koko (thrombosis).

Hoʻokaʻawale ʻia ke ʻano o ka thrombosis a me ka hemostasis i ʻekolu mau ʻanuʻu:

Hoʻokomo nui ʻia ka hemostasis mua i ka paia o ka moku, nā ʻāpana endothelial, a me nā platelets.Ma hope o ka ʻeha moku, ʻākoakoa koke nā platelets e hoʻōki i ke koko.

ʻO ka hemostasis lua, i ʻike ʻia hoʻi he plasma hemostasis, hoʻāla i ka ʻōnaehana coagulation e hoʻohuli i ka fibrinogen i loko o ka fibrin cross-linked insoluble, e hana ana i nā clots nui.

ʻO ka fibrinolysis, ka mea e wāwahi ai i ka fibrin clot a hoʻihoʻi i ke kahe koko maʻamau.

Hoʻoponopono pololei ʻia kēlā me kēia ʻanuʻu e mālama i kahi kūlana kaulike.ʻO nā hemahema i kekahi loulou e alakaʻi i nā maʻi pili.

ʻO nā maʻi kahe koko he huaʻōlelo maʻamau no nā maʻi i hoʻokumu ʻia e nā ʻano hana hemostasis ʻano.Hiki ke hoʻokaʻawale ʻia nā maʻi koko i ʻelua mau ʻāpana: hereditary a loaʻa, a ʻo nā hōʻike lapaʻau ka nui o ke koko ma nā ʻāpana like ʻole.ʻO nā maʻi kahe koko, ka hemophilia A maʻamau (ka hemahema o ka coagulation factor VIII), hemophilia B (ka hemahema o ka coagulation factor IX) a me nā mea ʻino o ka coagulation i hoʻokumu ʻia e ka fibrinogen deficiency;loaʻa nā maʻi kahe koko, maʻamau Aia ka nele o ka coagulation factor e pili ana i ka vitamina K, nā kumu coagulation abnormal i hoʻokumu ʻia e ka maʻi ate, etc.

Hoʻokaʻawale ʻia nā maʻi thromboembolic i ka thrombosis arterial a me ka thromboembolism venous (venousthromboembolism, VTE).ʻOi aku ka maʻamau o ka thrombosis i loko o nā aʻa coronary, nā ʻaʻa cerebral, nā ʻaʻa mesenteric, a me nā aʻa o nā lālā, a me nā mea ʻē aʻe. ;ʻo ia ke kumu o ka ischemia a me ka hypoxia i loko o nā ʻāpana hāʻawi koko kūpono ʻO ke kino kūpono ʻole, ke ʻano o ka ʻiʻo a me ka hana, e like me ka myocardial infarction, heart failure, cardiogenic shock, arrhythmia, disturbance of consciousness and hemiplegia, etc.;ʻO ka hoʻokahe ʻana o ka thrombus ke kumu o ka cerebral embolism, renal embolism, splenic embolism a me nā hōʻailona a me nā hōʻailona e pili ana.ʻO ka thrombosis Venous ka ʻano maʻamau o ka thrombosis vein hohonu ma nā ʻaoʻao haʻahaʻa.He mea maʻamau ia i nā veins hohonu e like me ka popliteal vein, femoral vein, mesenteric vein, a me portal vein.ʻO nā hōʻike intuitive ka pehu kūloko a me ka mānoanoa like ʻole o nā ʻaoʻao haʻahaʻa.ʻO ka Thromboembolism e pili ana i ka wehe ʻana o ka thrombus mai ka wahi i hoʻokumu ʻia ai, kahi ʻāpana a i ʻole ka hoʻopaʻa ʻana i kekahi mau kīʻaha koko i ka wā o ka neʻe ʻana me ke kahe koko, e hoʻoulu ai i ka ischemia, hypoxia, necrosis (arterial thrombosis) a me ka congestion, edema ( pathological process of venous thrombosis) .Ma hope o ka hāʻule ʻana o ka thrombosis vein hohonu o ka ʻaoʻao haʻahaʻa, hiki iā ia ke komo i ke aʻa pulmonary me ke kahe koko, a ʻike ʻia nā hōʻailona a me nā hōʻailona o ka pulmonary embolism.No laila, he mea nui ka pale ʻana i ka thromboembolism venous.