Loaʻa ʻia ʻo D-dimer mai ka ʻāpana fibrin i hoʻoheheʻe ʻia e ka plasmin.Hōʻike nui ia i ka hana lytic o ka fibrin.Hoʻohana nui ʻia ia i ka ʻike o ka thromboembolism venous, thrombosis vein hohonu a me ka embolism pulmonary i ka hana lapaʻau.ʻAʻole maikaʻi ka hōʻike qualitative D-dimer, inā ʻoi aku ka liʻiliʻi o ka hoʻokolohua quantitative ma mua o 200μg/L.

ʻIke pinepine ʻia ka D-dimer a i ʻole nā ​​hopena hoʻāʻo maikaʻi i nā maʻi e pili ana i ka hyperfibrinolysis lua, e like me ka hypercoagulable state, disseminated intravascular coagulation, renal disease, organ transplant rejection, and thrombolytic therapy.Eia kekahi, ke hoʻoikaika ʻia ka thrombosis i loko o nā kīʻaha koko o ke kino, a i ʻole nā ​​​​maʻi i hui pū ʻia me ka hana fibrinolytic, e hoʻonui nui ʻia ʻo D-dimer.ʻO nā maʻi maʻamau e like me ka myocardial infarction, pulmonary embolism, thrombosis vein hohonu haʻahaʻa, cerebral infarction Etc.;ʻO kekahi mau maʻi, ʻokiʻoki, nā maʻi maʻi maʻi, a me ka necrosis o ka ʻiʻo e alakaʻi i ka hoʻonui D-dimer;Eia kekahi, ʻo kekahi mau maʻi autoimmune kanaka, e like me ka rheumatic endocarditis, rheumatoid arthritis, systemic Lupus erythematosus, etc., hiki ke hoʻonui i ka D-dimer.

Ma waho aʻe o ka ʻike ʻana i nā maʻi, hiki i ka ʻike nui o D-dimer ke hoʻohālikelike i ka hopena thrombolytic o nā lāʻau lapaʻau i ka hana lapaʻau.ʻO nāʻano o nā maʻi, a me nā mea'ē aʻe, he mea kōkua.

I ka hihia o D-dimer kiʻekiʻe, aia ke kino i kahi kiʻekiʻe o ka thrombosis.I kēia manawa, pono e ʻike koke ʻia ka maʻi mua, a e hoʻomaka ka papahana pale thrombosis e like me ka helu DVT.Hiki ke koho ʻia kekahi mau lāʻau lapaʻau no ka anticoagulation therapy, e like me ka subcutaneous injection o ka haʻahaʻa molecular heparin calcium a i ʻole rivaroxaban, i loaʻa kahi hopena pale i ka hoʻokumu ʻana o ka thrombosis.Pono ka poʻe me nā maʻi thrombotic e hoʻopaʻa i ka maʻi thrombolytic i ka wā hiki loa i loko o ka manawa gula, a nānā i kēlā me kēia manawa i ka D-dimer.