ʻO APTT ka pōkole Pelekane o ka manawa prothrombin i hoʻoikaika ʻia.ʻO ka APTT kahi hōʻike hōʻike e hōʻike ana i ke ala coagulation endogenous.Hōʻike ka APTT lōʻihi i ka hana ʻole o kekahi mea hoʻohui koko i loko o ke ala coagulation endogenous kanaka.Ma hope o ka hoʻolōʻihi ʻia ʻana o ka APTT, e loaʻa i ka mea maʻi nā hōʻailona koko.No ka laʻana, ʻo ka poʻe maʻi me ka hemophilia A, ka hemophilia B, a me ka maʻi von Willebrand e hoʻolōʻihi i ka APTT, a e loaʻa i ka mea maʻi ka ecchymosis ma ka ʻili a me ka mucous membrane, a me ke koko koko., hui koko, hematoma, etc. 'Oi aku no ka poe ma'i me ka hemophilia A, hui deformities a me ka muscle atrophy e waiho pinepine ma hope o ka hematoma e komo ma muli o synovitis i hoʻokumu 'ia e ka hui koko, ka mea i koʻikoʻi i ke olakino.Eia kekahi, ʻo ka hoʻolaha ʻana o ka coagulation intravascular, ka maʻi ate koʻikoʻi a me nā maʻi ʻē aʻe e hoʻolōʻihi i ka APTT, kahi e hōʻeha ai i ke kino o ke kanaka.
ʻO ka waiwai kiʻekiʻe o Aptt e hōʻike ana e pilikia paha ka mea maʻi i nā maʻi koko.ʻO nā maʻi hoʻokahe koko maʻamau, ʻo ia ka congenital coagulation factor deficiency a me ka hemophilia.ʻO ka lua, ua manaʻo ʻia ʻo ia ke kumu o ka maʻi ate a i ʻole ka jaundice obstructive a i ʻole ka maʻi thrombotic.ʻAʻole hoʻi i kāpae ʻia ke kumu o ka hopena o nā kumu lāʻau lapaʻau, e like me ka hoʻohana lōʻihi o nā lāʻau anticoagulant.ʻO ka maʻi maʻi, hiki ke hoʻohana ʻia ka hoʻāʻo aptt e hoʻoholo inā he maʻamau ka hana coagulation i loko o ke kino o ka mea maʻi.Inā ma muli o ke ʻano o ka hemophilia, pono ia e hahai i ka ʻōlelo a ke kauka e hoʻōki i ke koko a hoʻohana paha i ka mālama prothrombin complex.