1. He ho'ā'o ka Plasma D-dimer assay e ho'omaopopo i ka hana fibrinolytic lua.

Manaʻo nānā: Ua uhi ʻia ka anti-DD monoclonal antibody ma nā ʻāpana latex.Inā loaʻa ka D-dimer i loko o ka plasma receptor, e kū mai ana ka hopena antigen-antibody, a e hōʻuluʻulu ʻia nā ʻāpana latex.Eia nō naʻe, hiki i kēia hoʻāʻo ke kūpono no kēlā me kēia koko me ka hoʻokumu ʻana o ke koko, no laila he haʻahaʻa haʻahaʻa a me ka ʻike kiʻekiʻe.

2. Elua kumu o D-dimer in vivo

(1) Hypercoagulable state a me ka hyperfibrinolysis lua;

(2) thrombolysis;

Hōʻike nui ka D-dimer i ka hana fibrinolytic.Hoʻonui a maikaʻi paha i ʻike ʻia i ka hyperfibrinolysis lua, e like me ke kūlana hypercoagulable, hoʻolaha ʻia ka coagulation intravascular, maʻi renal, hōʻole ʻia o ke kino, thrombolytic therapy, etc.

3. ʻOiai ka lōʻihi o ka thrombosis ikaika a me ka hana fibrinolytic i loko o nā kīʻaha koko o ke kino, e piʻi aʻe ka D-dimer.

No ka laʻana: myocardial infarction, cerebral infarction, pulmonary embolism, venous thrombosis, surgery, tumor, disseminated intravascular coagulation, infection and tissue necrosis hiki ke alakaʻi i ka hoʻonui D-dimer.Maikaʻi no nā poʻe maʻi maʻi a me nā maʻi maʻi, ma muli o ka bacteremia a me nā maʻi ʻē aʻe, maʻalahi ke kumu o ka coagulation koko maʻamau a alakaʻi i ka hoʻonui D-dimer.

4. ʻAʻole pili ka kikoʻī i hōʻike ʻia e D-dimer i ka hana ma kahi maʻi kūikawā, akā i nā ʻano pathological maʻamau o kēia hui nui o nā maʻi me ka coagulation a me ka fibrinolysis.

ʻO ke kumu, ʻo ka hoʻokumu ʻana o ka fibrin cross-linked thrombosis.Eia nō naʻe, nui nā maʻi lapaʻau e hiki ke hoʻāla i ka ʻōnaehana coagulation i ka wā o ka ulu ʻana o ka maʻi.Ke hana ʻia ka fibrin cross-linked, e hoʻāla ʻia ka ʻōnaehana fibrinolytic a e hydrolyzed ka fibrin cross-linked i mea e pale ai i kāna "hui nui".(ka thrombus koʻikoʻi ma ke kino), ka hopena i ka D-dimer kiʻekiʻe.No laila, ʻo ka D-dimer kiʻekiʻe ʻaʻole ia he thrombosis koʻikoʻi.No kekahi mau maʻi a kanaka paha, he kaʻina hana pathological paha.