ʻO nā ʻōlelo hōʻike hoʻāʻo hana coagulation me ka prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen (FIB), Clotting time (CT) a me International normalized ratio (INR), etc. koho ʻia e hana i kahi pūʻolo, i kapa ʻia ʻo coagulation X item.Ma muli o nā ʻano ʻike like ʻole i hoʻohana ʻia e nā haukapila like ʻole, ʻokoʻa nā pae kuhikuhi.

ʻO ka manawa PT-prothrombin

ʻO ka PT e pili ana i ka hoʻohui ʻana i ka mea kiko (TF a i ʻole ka thromboplastin kiko) a me Ca2+ i ka plasma e hoʻomaka ai i ka ʻōnaehana coagulation extrinsic a nānā i ka manawa coagulation o ka plasma.ʻO PT kekahi o nā hoʻāʻo screening maʻamau i hoʻohana ʻia i ka hana lapaʻau e loiloi i ka hana o ke ala coagulation extrinsic.He 10 a 14 kekona ka helu kuhikuhi maʻamau.

APTT - ho'ā 'ia hapa thromboplastin manawa

ʻO ka APTT e hoʻohui i ka XII mea hoʻoulu, Ca2 +, phospholipid i ka plasma e hoʻomaka i ke ala coagulation endogenous plasma, a nānā i ka manawa coagulation plasma.ʻO APTT kekahi o nā hoʻokolohua hoʻomaʻamaʻa maʻamau i hoʻohana ʻia i ka hana lapaʻau e loiloi i ka hana o ke ala coagulation intrinsic.He 32 a 43 kekona ka helu kuhikuhi maʻamau.

INR - Lakiō maʻamau maʻamau

ʻO ka INR ka mana ISI o ka ratio o ka PT o ka mea maʻi i ho'āʻoʻia i ka PT o ka mana maʻamau (ʻo ISI kahi helu hoʻonaʻauao honua, a ua calibrated ka reagent e ka mea hana i ka wā e haʻalele ai i ka hale hana).Ua hoʻāʻo ʻia ka plasma like me nā reagents ISI ʻē aʻe i nā laboratories like ʻole, a he ʻokoʻa loa nā hopena waiwai PT, akā like nā helu INR i ana ʻia, i hoʻohālikelike ʻia nā hopena.ʻO ka helu kuhikuhi maʻamau ʻo 0.9 a 1.1.

TT-thrombin manawa

ʻO TT ka hoʻohui o ka thrombin maʻamau i ka plasma e ʻike i ke kolu o ka pae o ke kaʻina coagulation, e hōʻike ana i ke kiʻekiʻe o ka fibrinogen i ka plasma a me ka nui o nā mea like heparin i loko o ka plasma.He 16 a 18 kekona ka helu kuhikuhi maʻamau.

FIB-fibrinogen

E hoʻohui ʻo FIB i kahi nui o ka thrombin i ka plasma i hoʻāʻo ʻia e hoʻohuli i ka fibrinogen i loko o ka plasma i fibrin, a helu i ka ʻike o ka fibrinogen ma o ke kumu turbidimetric.ʻO ka helu kuhikuhi maʻamau he 2 a 4 g/L.

FDP-plasma fibrin degradation huahana

He huaʻōlelo maʻamau ka FDP no nā huahana degradation i hana ʻia ma hope o ka hoʻoheheʻe ʻia ʻana o ka fibrin a i ʻole fibrinogen ma lalo o ka hana a ka plasmin i hana ʻia i ka wā hyperfibrinolysis.ʻO ka helu kuhikuhi maʻamau he 1 a 5 mg/L.

CT-coagulation manawa

ʻO ka CT e pili ana i ka manawa e haʻalele ai ke koko i nā kīʻaha koko a coagulates in vitro.ʻO ia ka mea e hoʻoholo ai inā nele nā ​​mea coagulation like ʻole i ke ala coagulation intrinsic, inā he maʻamau kā lākou hana, a i ʻole he piʻi ʻana o nā mea anticoagulant.