Nā Kūlana no ka Thrombosis


Mea kākau: Hope   

I loko o ka puʻuwai ola a i ʻole ka ipu koko, ʻo kekahi mau mea i loko o ke koko e hoʻohui a hoʻopaʻa ʻia e hana i kahi paʻa paʻa, i kapa ʻia ʻo thrombosis.Ua kapa ʻia ka nuipa paʻa i hana ʻia he thrombus.

Ma lalo o nā kūlana maʻamau, aia nā ʻōnaehana coagulation a me nā ʻōnaehana anticoagulation (fibrinolysis system, a i ʻole fibrinolysis system no ka pōkole) i loko o ke koko, a mālama ʻia ke koena ikaika ma waena o nā mea ʻelua, i mea e hōʻoia ai i ka holo ʻana o ke koko i loko o ka ʻōnaehana cardiovascular i kahi wai. mokuʻāina.kahe mau

Hoʻohana mau ʻia nā kumu coagulation i loko o ke koko, a hana ʻia kahi thrombin liʻiliʻi e hana i kahi fibrin liʻiliʻi, i waiho ʻia ma ka intima o ke kīʻaha koko, a laila hoʻoheheʻe ʻia e ka ʻōnaehana fibrinolytic i hoʻāla ʻia.I ka manawa like, hoʻomau mau ʻia nā mea coagulation i hoʻāla ʻia a hoʻomaʻemaʻe ʻia e ka ʻōnaehana macrophage mononuclear.

Eia nō naʻe, ma lalo o nā kūlana pathological, ua hoʻopau ʻia ke koena ikaika ma waena o ka coagulation a me ka anticoagulation, ʻoi aku ka mana o ka hana o ka ʻōnaehana coagulation, a me ke koko coagulates i loko o ka ʻōnaehana cardiovascular e hana i ka thrombus.

Loaʻa i ka Thrombosis nā kūlana ʻekolu:

1. ʻO ka ʻeha o ka puʻuwai a me ke kīʻaha koko

ʻO ka intima o ka puʻuwai maʻamau a me nā kīʻaha koko he paʻa a maʻalahi, a hiki i nā cell endothelial paʻa ke kāohi i ka platelet adhesion a me ka anticoagulation.Ke hoʻopōʻino ʻia ka membrane o loko, hiki ke hoʻāla ʻia ka ʻōnaehana coagulation ma nā ʻano he nui.

Hoʻokuʻu ka intima mua i pōʻino i ke kumu coagulation kiko (coagulation factor III), e hoʻāla i ka ʻōnaehana coagulation extrinsic.
ʻO ka lua, ma hope o ka hoʻopōʻino ʻia ʻana o ka intima, e loaʻa ana nā cell endothelial i ka degeneration, necrosis, a me ka hoʻoheheʻe ʻana, e hōʻike ana i nā fiber collagen ma lalo o ka endothelium, a laila e hoʻāla ai i ka coagulation factor XII o ka ʻōnaehana coagulation endogenous a hoʻomaka i ka ʻōnaehana coagulation endogenous.Eia kekahi, lilo ka intima i pōʻino, kahi kūpono i ka waiho ʻana o ka platelet a hoʻopili.Ma hope o ka haki ʻana o nā platelets i hoʻopaʻa ʻia, hoʻokuʻu ʻia nā ʻano platelet like ʻole, a hoʻāla ʻia ke kaʻina coagulation holoʻokoʻa, e hoʻoulu ai i ke koko a hana i kahi thrombus.
Hiki i nā ʻano mea like ʻole ke kino, kemika a me nā mea ola ke hoʻopilikia i ka intima cardiovascular, e like me ka endocarditis i ka puaʻa erysipelas, pulmonary vasculitis i ka bovine pneumonia, equine parasitic arteritis, hoʻopiʻi pinepine ʻia i ka ʻāpana like o ka vein, ʻeha a me ka ʻeha o ka paia o ka moku koko. i ka wā ʻoki.

2. Hoʻololi i ke kūlana kahe koko

ʻO ka mea nui e pili ana i ke kahe o ke koko, ka hoʻokumu ʻana o ka vortex a me ka pau ʻana o ke kahe koko.
Ma lalo o nā kūlana maʻamau, wikiwiki ke kahe o ke koko, a ʻo nā ʻulaʻula ʻulaʻula, nā platelets a me nā mea ʻē aʻe i hoʻopaʻa ʻia i waenakonu o ke kīʻaha koko, i kapa ʻia ke kahe axial;i ka wā e lohi ai ke kahe o ke koko, e kahe ana ke koko ʻulaʻula a me nā platelets kokoke i ka paia o ke kīʻaha koko, i kapa ʻia ke kahe ʻaoʻao, kahi e hoʻonui ai i ka thrombosis.pilikia e puka mai ana.
Hoʻolohi ʻia ke kahe o ke koko, a he hypoxic koʻikoʻi nā cell endothelial, e hoʻoulu ai i ka degeneration a me ka necrosis o nā cell endothelial, ka nalowale o kā lākou hana o ka synthesizing a me ka hoʻokuʻu ʻana i nā mea anticoagulant, a me ka ʻike ʻana o ka collagen, ka mea e hoʻāla ai i ka ʻōnaehana coagulation a hoʻoikaika. thrombosis.
Hiki i ke kahe lohi o ke koko ke maʻalahi i ka thrombus i hana ʻia e hoʻoponopono i ka paia o ka moku koko a hoʻomau i ka hoʻonui.

No laila, ʻike pinepine ʻia ka thrombus i loko o nā veins me ka lohi o ke kahe ʻana o ke koko a hiki i ka eddy currents (ma nā venous valves).He wikiwiki ke kahe ʻana o ke koko aortic, a ʻike pinepine ʻia ka thrombus.Wahi a nā helu helu, ʻo ka loaʻa ʻana o ka thrombosis venous he 4 mau manawa ma mua o ka thrombosis arterial, a ʻo ka thrombosis venous e hana pinepine ʻia i ka hāʻule ʻana o ka naʻau, ma hope o ke ʻoki ʻana a i ʻole nā ​​holoholona maʻi e moe ana i ka pūnana no ka manawa lōʻihi.
No laila, he mea koʻikoʻi ke kōkua ʻana i nā holoholona maʻi e moe ana i lalo no ka manawa lōʻihi a ma hope o ke ʻoki ʻana e hana i kekahi mau hana kūpono e pale ai i ka thrombosis.
3. Hoʻololi i nā waiwai koko.

ʻO ka mea nui e pili ana i ka hoʻonui ʻana i ke koko coagulation.E like me ke ahi nui, ka wai maloʻo, a me nā mea ʻē aʻe e noʻonoʻo ai i ke koko, trauma nui, postpartum, a me ke kahe nui o ke koko ma hope o nā hana nui hiki ke hoʻonui i ka helu o nā platelets i loko o ke koko, hoʻonui i ka viscosity koko, a hoʻonui i ka ʻike o fibrinogen, thrombin a me nā mea coagulation ʻē aʻe. i ka plasma Hoʻonui.Hiki i kēia mau mea ke hoʻoikaika i ka thrombosis.

Hōʻuluʻulu manaʻo

ʻO nā mea ʻekolu i luna e noho pū pinepine i ke kaʻina o ka thrombosis a pili kekahi i kekahi, akā he mea nui kekahi mea i nā pae like ʻole o ka thrombosis.

No laila, i ka hoʻomaʻamaʻa lapaʻau, hiki ke pale i ka thrombosis ma ka hopu pololei ʻana i nā kūlana o ka thrombosis a me ka lawe ʻana i nā ana kūpono e like me ke kūlana maoli.E like me ke kaʻina hana e hoʻolohe i ka hana mālie, pono e ho'āʻo e pale i ka pōʻino i nā kīʻaha koko.No ka hoʻohana ʻana i ka intravenous injection no ka manawa lōʻihi, e pale i ka hoʻohana ʻana i ka pūnaewele like, etc.