Hiki ke ʻike inā he hana coagulation maʻi ka mea maʻi ma mua o ke ʻoki ʻana, e pale pono i nā kūlana i manaʻo ʻole ʻia e like me ke kahe ʻole ʻana o ke koko i ka wā a ma hope o ke ʻoki ʻana, i loaʻa ai ka hopena ʻoi loa.
Hoʻokō ʻia ka hana hemostatic o ke kino e ka hui pū ʻana o nā platelets, coagulation system, fibrinolytic system and vascular endothelial system.I ka wā ma mua, ua hoʻohana mākou i ka manawa koko e like me ka hoʻāʻo ʻana no ka hemostatic function defects, akā ma muli o kona haʻahaʻa haʻahaʻa, maikaʻi ʻole ka naʻau, a me ka hiki ʻole ke noʻonoʻo i ka ʻike a me ka hana o nā kumu coagulation, ua hoʻololi ʻia e nā hoʻokolohua hana coagulation.ʻO nā hoʻokolohua hana coagulation ka nui o ka plasma prothrombin time (PT) a me ka hana PT i helu ʻia mai ka PT, international normalized ratio (INR), fibrinogen (FIB), activated partial thromboplastin time (APTT) a me ka plasma thrombin time (TT).
Hōʻike ka PT i ka hana o ka ʻōnaehana coagulation extrinsic.ʻIke ʻia ka PT lōʻihi i ka congenital coagulation factor II, V, VII, a me X ka ho'ēmi ʻana, fibrinogen deficiency, loaʻa ka coagulation factor deficiency (DIC, primary hyperfibrinolysis, obstructive jaundice, vitamin K deficiency, and anticoagulant substances in the blood circulation. PT shortening is ʻike nui ʻia i ka piʻi ʻana o ka coagulation factor V, DIC mua, nā maʻi thrombotic, nā contraceptive waha, a me nā mea ʻē aʻe; hiki ke hoʻohana ʻia ka nānā ʻana i ka PT e like me ka nānā ʻana i nā lāʻau anticoagulant waha.
ʻO ka APTT ka hōʻike hōʻike hōʻoia pono loa no ka hemahema o ka mea coagulation endogenous.ʻIke nui ʻia ka APTT lōʻihi i ka hemophilia, DIC, ka maʻi ate, a me ka hoʻololi nui ʻana o ke koko panakō.ʻIke nui ʻia ka APTT pōkole i DIC, prothrombotic state, a me nā maʻi thrombotic.Hiki ke hoʻohana ʻia ka APTT ma ke ʻano he hōʻailona nānā no ka maʻi heparin.
ʻIke ʻia ka hoʻolōʻihi ʻana o TT i ka hypofibrinogenemia a me dysfibrinogenemia, hoʻonui i ka FDP i ke koko (DIC), a me ka loaʻa ʻana o ka heparin a me nā mea heparinoid i loko o ke koko (e laʻa, i ka wā heparin therapy, SLE, maʻi ate, etc.).
Aia kekahi maʻi pilikia i loaʻa i nā hoʻokolohua hoʻokolohua preoperative, a ua hoʻolōʻihi ʻia nā hopena o ka hoʻāʻo coagulation PT a me APTT, a ua kānalua ʻia ʻo DIC i ka mea maʻi.Ma lalo o ka ʻōlelo aʻoaʻo o ka hale hana, ua hana ka mea maʻi i kahi ʻano o nā hoʻokolohua DIC a ua maikaʻi nā hopena.ʻAʻohe hōʻailona maopopo o DIC.Inā ʻaʻole i loaʻa i ka mea maʻi kahi hoʻāʻo coagulation, a ʻoki pololei ʻia, e pōʻino nā hopena.Hiki ke loaʻa ka nui o ia mau pilikia mai ka hoʻāʻo ʻana i ka hana coagulation, i kūʻai hou aku i ka manawa no ka ʻike ʻana a me ka mālama ʻana i nā maʻi.ʻO ka hoʻāʻo ʻana o ka coagulation series kahi hoʻokolohua koʻikoʻi no ka hana coagulation o nā maʻi, hiki ke ʻike i ka hana coagulation maʻamau i nā mea maʻi ma mua o ke ʻoki ʻana, a pono e uku nui ʻia.
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