Loaʻa i ke kino maʻamau ka ʻōnaehana coagulation a me ka anticoagulation.Mālama ka ʻōnaehana coagulation a me ka ʻōnaehana anticoagulation i kahi kaulike ikaika e hōʻoia i ka hemostasis o ke kino a me ke kahe ʻana o ke koko.I ka wā e hoʻopilikia ʻia ai ke kaulike o ka coagulation a me ka anticoagulation, e alakaʻi ia i ke koko a me ka thrombosis.

1. Ka hana coagulation o ke kino

ʻO ka ʻōnaehana coagulation ka nui o nā kumu coagulation.ʻO nā mea i pili pono i ka coagulation ua kapa ʻia nā mea coagulation.He 13 mau kumu coagulation i ʻike ʻia.

Aia nā ala ho'āla endogenous a me nā ala hoʻoulu exogenous no ka hoʻouluʻana i nā kumu coagulation.

Ke manaʻoʻiʻo ʻia nei ʻo ka hoʻāla ʻana o ka ʻōnaehana coagulation exogenous i hoʻomaka ʻia e ka tissue factor ke kuleana nui i ka hoʻomaka ʻana o ka coagulation.ʻO ka pilina pili ma waena o nā ʻōnaehana coagulation o loko a me waho he mea nui i ka hoʻomaka ʻana a me ka mālama ʻana i ke kaʻina coagulation.

2. Ka hana anticoagulant o ke kino

Aia ka ʻōnaehana anticoagulation i ka ʻōnaehana anticoagulation cellular a me ka ʻōnaehana anticoagulation wai kino.

① Pūnaehana anticoagulation

E pili ana i ka phagocytosis o ka coagulation factor, tissue factor, prothrombin complex and soluble fibrin monomer e ka mononuclear-phagocyte system.

② Pūnaehana anticoagulation wai kino

E komo pū ana: nā mea hoʻopaneʻe serine protease, nā mea hoʻopaneʻe protease i hoʻokumu ʻia i ka protein C a me nā mea hoʻopaneʻe ala ala kiko (TFPI).

3. Pūnaehana Fibrinolytic a me kāna mau hana

Hoʻokomo nui i ka plasminogen, plasmin, plasminogen activator a me ka fibrinolysis inhibitor.

ʻO ke kuleana o ka ʻōnaehana fibrinolytic: hoʻopau i nā clots fibrin a hōʻoia i ka holo ʻana o ke koko;komo i ka hoʻoponopono ʻana i ka ʻiʻo a me ka hoʻōla hou ʻana o nā vascular.

4. ʻO ke kuleana o nā pūnaewele endothelial vascular i ke kaʻina o ka coagulation, anticoagulation a me ka fibrinolysis

① E hana i nā ʻano mea like ʻole;

②Hoʻoponopono i ka coagulation koko a me ka hana anticoagulation;

③Hoʻoponopono i ka hana o ka ʻōnaehana fibrinolysis;

④ Hoʻoponopono i ka ʻehaʻeha o ke koko;

⑤E komo i ka uwao o ka mumū;

⑥E mālama i ka hana o ka microcirculation, etc.

ʻO ka coagulation a me nā maʻi anticoagulant

1. Nā mea ʻino i nā kumu coagulation.

2. ʻO keʻano o nā mea anticoagulant i loko o ka plasma.

3. ʻAʻole kūpono o ka mea fibrinolytic i loko o ka plasma.

4. ʻO nā meaʻino o ke koko.

5. Nā kīʻaha koko like ʻole.