01. Sanin farko da D-dimer, FDP

1. FDP shine kalmar gabaɗaya don nau'ikan samfuran lalacewa na fibrin da fibrinogen ƙarƙashin aikin plasmin, wanda galibi yana nuna babban matakin fibrinolytic na jiki;

2. D-dimer wani ƙayyadaddun samfurin lalacewa ne na fibrin mai haɗin gwiwa a ƙarƙashin aikin plasmin, kuma karuwar matakinsa yana nuna kasancewar hyperfibrinolysis na biyu;

02. Aikace-aikacen asibiti na D-dimer da FDP

Ban da thrombosis na jini (VTE ya haɗa da DVT, PE)

Daidaiton D-dimer korau ware na zurfin jijiya thrombosis (DVT) zai iya kaiwa 98% -100%

Ana iya amfani da gano D-dimer don kawar da thrombosis na venous

♦ Muhimmanci a cikin ganewar asali na DIC

1. DIC wani tsari ne mai rikitarwa na pathophysiological da kuma mummunan ciwo na thrombo-hemorrhagic na asibiti.Yawancin DICs suna da saurin farawa, cututtuka masu rikitarwa, saurin haɓakawa, da wuyar ganewar asali, da haɗari mai haɗari.Idan ba a gano cutar da wuri ba kuma a bi da ita yadda ya kamata, Sau da yawa yana jefa rayuwar majiyyaci cikin haɗari;

2. D-dimer zai iya nuna tsananin DIC zuwa wani matsayi, FDP za a iya amfani da shi don lura da ci gaban cutar bayan an tabbatar da ganewar asali, kuma antithrombin (AT) yana taimakawa wajen fahimtar tsananin cutar da kuma tasirin cutar. Maganin heparin Haɗin D-dimer, FDP da gwajin AT sun zama mafi kyawun nuni don gano DIC.

♦Muhimmanci a cikin ƙwayoyin cuta masu cutarwa

1. M ciwace-ciwacen daji suna da alaƙa da rashin aiki na hemostasis.Ko da kuwa mummunan ciwace-ciwacen ciwace ko cutar sankarar bargo, marasa lafiya za su sami yanayin hypercoagulable mai tsanani ko thrombosis.Adenocarcinoma mai rikitarwa ta hanyar thrombosis shine mafi yawan;

2. Yana da kyau a nanata cewa thrombosis na iya zama farkon alamar ciwon daji.A cikin marasa lafiya masu zurfin jijiya mai zurfi waɗanda suka kasa gano abubuwan haɗari na thrombosis na jini, akwai yuwuwar samun ƙari.

♦Muhimmancin asibiti na wasu cututtuka

1. Kula da maganin maganin thrombolytic

A lokacin jiyya, idan adadin maganin thrombolytic bai isa ba kuma thrombus ba a narkar da shi gaba daya, D-dimer da FDP za su kula da babban matakin bayan sun kai ganiya;yayin da yawan ƙwayar thrombolytic zai kara haɗarin zubar jini.

2. Muhimmancin ƙananan kwayoyin heparin magani bayan tiyata

Marasa lafiya da ke fama da rauni / tiyata galibi ana bi da su tare da maganin rigakafin jijiyoyi.

Gabaɗaya, ainihin kashi na ƙananan ƙwayoyin heparin shine 2850IU/d, amma idan matakin D-dimer na majiyyaci shine 2ug/ml a rana ta 4 bayan tiyata, ana iya ƙara adadin zuwa sau 2 a rana.

3. Aortic dissection (AAD)

AAD shine sanadin gama gari na mutuwa kwatsam a cikin marasa lafiya.Binciken farko da magani na iya rage yawan mace-mace na marasa lafiya da rage haɗarin likita.

Hanyar da za ta yiwu don haɓaka D-dimer a cikin AAD: Bayan tsakiyar Layer na bangon jirgin ruwa aortic ya lalace saboda dalilai daban-daban, bangon jijiyoyin jini ya rushe, yana sa jini ya mamaye ciki da na waje don samar da "ragon karya" , saboda jinin gaskiya da ƙarya a cikin rami Akwai babban bambanci a cikin saurin gudu, kuma saurin gudu a cikin rami na ƙarya yana da jinkirin jinkirin, wanda zai iya haifar da thrombosis cikin sauƙi, ya sa tsarin fibrinolytic ya kunna, kuma a ƙarshe yana ingantawa. karuwar matakin D-dimer.

03. Abubuwan da suka shafi D-dimer da FDP

1. Halayen Physiological

Maɗaukaki: Akwai manyan bambance-bambance a cikin shekaru, mata masu juna biyu, motsa jiki mai tsanani, haila.

2.Tasirin cuta

Matsayi mai girma: bugun jini na cerebrovascular, maganin thrombolytic, kamuwa da cuta mai tsanani, sepsis, gangrene nama, preeclampsia, hypothyroidism, cututtukan hanta mai tsanani, sarcoidosis.

3.Hyperlipidemia da illar sha

Maɗaukaki: masu sha;

Rage: hyperlipidemia.

4. Tasirin magunguna

Haɓaka: heparin, magungunan antihypertensive, urokinase, streptokinase da staphylokinase;

Ragewa: maganin hana haihuwa na baka da estrogen.
04. Takaitawa

Gano D-dimer da FDP lafiyayye ne, mai sauƙi, sauri, tattalin arziki, kuma mai matuƙar kulawa.Dukansu biyun za su sami nau'ikan canje-canje daban-daban a cikin cututtukan zuciya da jijiyoyin jini, cututtukan hanta, cututtukan cerebrovascular, hauhawar jini mai haifar da ciki, da pre-eclampsia.Yana da mahimmanci a yi la'akari da tsananin cutar, kula da ci gaba da canji na cutar, da kuma kimanta tasirin maganin warkewa.tasiri.