Muhimmancin asibiti
Ainihin yana da ma'ana iri ɗaya da lokacin coagulation, amma tare da babban hankali.Yawancin hanyoyin tantancewar APTT da ake amfani da su a halin yanzu na iya zama mara kyau lokacin da yanayin coagulation na plasma ya yi ƙasa da 15% zuwa 30% na matakin al'ada.
(1) Tsawaita APTT: sakamakon APTT shine daƙiƙa 10 ya fi tsayi fiye da na yau da kullun.APTT ita ce mafi ingantaccen gwajin gwajin gwaji don ƙarancin coagulation factor kuma ana amfani dashi musamman don gano ƙananan haemophilia.Ko da yake factor Ⅷ: Ana iya gano matakan C a ƙasa da 25% na hemophilia A, rashin hankali ga hemophilia subclinical (factor Ⅷ> 25%) da masu ɗaukar hemophilia ba su da kyau.Ana kuma ganin sakamakon dadewa a cikin ma'ana Ⅸ (hemophilia B), Ⅺ da Ⅶ kasawa;lokacin da abubuwan da ke hana ƙin jini na jini kamar masu hana coagulation factor inhibitors ko matakan heparin sun karu, prothrombin, fibrinogen da factor V, rashi X kuma Yana iya tsawaita, amma hankali ya ɗan yi rauni;Hakanan ana iya ganin tsawaitawar APTT a cikin wasu marasa lafiya da ke fama da cutar hanta, DIC, da babban adadin jinin banki.
(2) APTT gajarta: gani a DIC, prethrombotic jihar da thrombotic cuta.
(3) Kula da jiyya na heparin: APTT yana da matukar damuwa ga tattarawar heparin na plasma, don haka jigon sa ido na dakin gwaje-gwaje ne da ake amfani da shi sosai a halin yanzu.A wannan lokacin, ya kamata a lura cewa sakamakon ma'aunin APTT dole ne ya kasance yana da alaƙar layi tare da haɗin jini na heparin a cikin kewayon warkewa, in ba haka ba bai kamata a yi amfani da shi ba.Gabaɗaya, yayin jiyya na heparin, yana da kyau a kula da APTT a 1.5 zuwa 3.0 sau fiye da na yau da kullun.
Binciken sakamako
A asibiti, ana amfani da APTT da PT a matsayin gwaje-gwajen gwaji don aikin coagulation na jini.Dangane da sakamakon aunawa, akwai kusan yanayi huɗu masu zuwa:
(1) Dukansu APTT da PT na al'ada ne: Sai dai ga mutane na yau da kullun, ana gani ne kawai a cikin rashi na FXIII na gado da na sakandare.Wadanda aka samu sun zama ruwan dare a cikin cututtukan hanta mai tsanani, ciwon hanta, cutar sankarar bargo, cutar sankarar bargo, anti-factor XIII antibody, autoimmune anemia da kuma cutar anemia.
(2) Tsawon APTT tare da PT na al'ada: Yawancin cututtukan jini suna haifar da lahani a cikin hanyar coagulation na ciki.Irin su hemophilia A, B, da kuma rashi factor Ⅺ;akwai anti-factor Ⅷ, Ⅸ, Ⅺ rigakafi a cikin jini.
(3) APTT na al'ada tare da PT mai tsawo: yawancin cututtukan jini da ke haifar da lahani a cikin hanyar coagulation na waje, kamar kwayoyin halitta da rashi factor VII.Wadanda aka samu sun zama ruwan dare a cikin cututtukan hanta, DIC, anti-factor VII antibodies a cikin jini da kuma maganin rigakafi na baka.
(4) Dukansu APTT da PT suna tsawaitawa: yawancin cututtukan jini da ke haifar da lahani a cikin hanyar haɗin gwiwa na gama gari, kamar kwayoyin halitta da rashi na X, V, II da I.Ana ganin waɗanda aka samu galibi a cikin cututtukan hanta da DIC, kuma ana iya rage abubuwan X da II lokacin da ake amfani da maganin hana jini na baka.Bugu da kari, idan akwai anti-factor X, anti-factor V da anti-factor II antibodies a cikin jini wurare dabam dabam, su ma suna tsawaita daidai da haka.Lokacin da ake amfani da heparin a asibiti, duka APTTT da PT suna tsawanta daidai da haka.