D-dimer an samo shi daga ɗigon fibrin mai haɗin giciye wanda ya narkar da plasmin.Yafi nuna aikin lytic na fibrin.An fi amfani dashi a cikin ganewar asali na thromboembolism venous, thrombosis mai zurfi da kuma ciwon huhu a cikin aikin asibiti.Gwajin ingancin D-dimer mara kyau ne, idan gwajin ƙididdigewa yakamata ya zama ƙasa da 200μg/L.

Ƙarar D-dimer ko sakamakon gwaji mai kyau ana gani sau da yawa a cikin cututtuka da ke da alaka da hyperfibrinolysis na biyu, irin su hypercoagulable state, yada coagulation na intravascular, cututtuka na koda, watsi da kwayoyin halitta, da kuma maganin thrombolytic.Bugu da ƙari, lokacin da aka kunna thrombosis a cikin jini na jiki, ko cututtuka tare da aikin fibrinolytic, D-dimer kuma za a ƙara karuwa sosai.Cututtuka na yau da kullun irin su ciwon zuciya na zuciya, bugun jini na huhu, thrombosis mai zurfi na jijiyoyi, raunin kwakwalwa da dai sauransu;wasu cututtuka, tiyata, cututtukan tumo, da necrosis na nama kuma suna haifar da karuwar D-dimer;Bugu da ƙari, wasu cututtuka na autoimmune na mutum, irin su endocarditis rheumatic, rheumatoid arthritis, Lupus erythematosus na tsarin jiki, da dai sauransu, na iya haifar da karuwar D-dimer.

Bugu da ƙari ga bincikar cututtuka, ƙididdigar ƙididdiga na D-dimer kuma na iya nuna yawan tasirin thrombolytic na kwayoyi a cikin aikin asibiti.Abubuwan da suka shafi cututtuka, da sauransu, duk suna da taimako.

A cikin yanayin haɓakar D-dimer, jiki yana cikin haɗarin thrombosis.A wannan lokacin, ya kamata a gano cutar ta farko da wuri-wuri, kuma a fara shirin rigakafin thrombosis bisa ga ma'aunin DVT.Za a iya zaɓar wasu magunguna don maganin hana zubar jini, kamar allurar subcutaneous na ƙananan ƙwayoyin heparin alli ko rivaroxaban, waɗanda ke da wani tasiri na rigakafi akan samuwar thrombosis.Wadanda ke da raunuka na thrombotic suna buƙatar ƙwayar thrombolytic da wuri-wuri a cikin lokacin zinariya, kuma a lokaci-lokaci duba D-dimer.