Thrombosis shine kawai tsarin daskarewar jini na jiki.Idan ba tare da thrombus ba, yawancin mutane za su mutu daga "haɓakar jini mai yawa".
Kowannenmu ya samu rauni kuma yana zubar da jini, kamar guntuwar jiki, wanda nan ba da jimawa ba zai zubar da jini.Amma jikin mutum zai kare kansa.Domin hana zubar jini har zuwa mutuwa, jinin zai rika taruwa a hankali a wurin da ake zubar da jini, wato jinin zai haifar da thrombus a cikin magudanar jini da ya lalace.Ta wannan hanyar, babu sauran zubar jini.
Lokacin da zubar jini ya tsaya, jikinmu zai narke thrombus a hankali, yana barin jinin ya sake zagayawa.
Tsarin da ke samar da thrombus ana kiransa tsarin coagulation;tsarin da ke cire thrombus ana kiransa tsarin fibrinolytic.Da zarar magudanar jini ya lalace a cikin jikin mutum, ana kunna tsarin coagulation nan da nan don hana ci gaba da zubar jini;da zarar thrombus ya faru, tsarin fibrinolytic wanda ke kawar da thrombus za a kunna don narkar da ɗigon jini.
Tsarukan biyu suna daidaita daidai gwargwado, suna tabbatar da cewa jini baya yin coagulation ko zubar jini da yawa.
Duk da haka, yawancin cututtuka za su haifar da aikin da ba a saba ba na tsarin coagulation, da kuma lalacewa ga intima na jini, kuma jinkirin jini zai sa tsarin fibrinolytic ya yi latti ko rashin isa ya narkar da thrombus.
Misali, a cikin myocardial infarction, akwai thrombosis a cikin jijiyoyin jini na zuciya.Yanayin magudanar jini yana da rauni sosai, akwai lalacewar intima iri-iri, kuma akwai ƙwanƙwasawa, tare da tsayawar jini, babu yadda za a yi na narkar da thrombus, kuma thrombus zai ƙara girma da girma.
Alal misali, a cikin mutanen da ke kwance na dogon lokaci, jinin gida yana tafiya a cikin kafafu yana raguwa, an lalata magudanar jini, kuma an samu thrombus.thrombus zai ci gaba da narkewa, amma saurin narkar da shi ba ya da sauri sosai, yana iya faduwa, ya koma cikin jijiya ta huhu tare da tsarin jini, ya makale a cikin jijiyar huhu, kuma yana haifar da kumburin huhu, wanda kuma yana da mutuwa.
A wannan lokacin, don tabbatar da lafiyar marasa lafiya, ya zama dole a yi amfani da thrombolysis ta hanyar wucin gadi da kuma allurar magungunan da ake amfani da su don inganta thrombolysis, kamar "urokinase".Koyaya, thrombolysis gabaɗaya yana buƙatar aiwatarwa cikin ɗan gajeren lokaci na thrombosis, kamar cikin sa'o'i 6.Idan ya dauki lokaci mai tsawo, ba zai narke ba.Idan kun ƙara yawan amfani da magungunan thrombolytic a wannan lokacin, yana iya haifar da zubar jini a wasu sassan jiki.
Ba za a iya narkar da thrombus ba.Idan ba a toshe shi gaba daya ba, ana iya amfani da “stent” don “jawo” magudanar jinin da aka toshe don tabbatar da kwararar jini mai santsi.
Duk da haka, idan an katange jirgin jini na dogon lokaci, zai haifar da ischemic necrosis na mahimman tsarin nama.A wannan lokacin, kawai ta hanyar "bypassing" sauran hanyoyin jini za a iya gabatar da su don "ba ruwa" wannan yanki wanda ya rasa jininsa.
Zubar da jini da coagulation, thrombosis da thrombolysis, shine ma'auni mai laushi wanda ke kula da ayyukan rayuwa na jiki.Ba ma wannan kadai ba, akwai ma’auni na basira da yawa a cikin jikin dan’adam, kamar jijiyar tausayi da jijiyar jijiyoyi, wadanda ke kula da sha’awar mutane ba tare da jin dadi ba;insulin da glucagon suna daidaita ma'auni na sukarin jinin mutane;Calcitonin da parathyroid hormone suna daidaita sukarin jinin mutane.
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