A rayuwa, babu makawa mutane za su yi karo da zubar jini lokaci zuwa lokaci.A cikin yanayi na al'ada, idan ba a kula da wasu raunuka ba, jinin zai yi taruwa a hankali, ya daina zubar da jini da kansa, kuma a ƙarshe ya bar ɓawon jini.Me yasa wannan?Wadanne abubuwa ne suka taka muhimmiyar rawa a cikin wannan tsari?Na gaba, bari mu bincika ilimin coagulation jini tare!

Kamar yadda kowa ya sani, jini yana yawo a cikin jikin dan Adam kullum a karkashin turawar zuciya don jigilar iskar oxygen, protein, ruwa, electrolytes da carbohydrates da jiki ke bukata.A karkashin yanayi na al'ada, jini yana gudana a cikin tasoshin jini.Lokacin da tasoshin jini suka lalace, jiki zai daina zubar jini da gudan jini ta hanyar amsawa da yawa.Ƙunƙarar jini na al'ada da hemostasis na jikin ɗan adam ya dogara ne akan tsari da aikin bangon jirgin ruwa mara kyau, aikin al'ada na abubuwan coagulation, da inganci da adadin platelet masu tasiri.

A cikin yanayi na al'ada, ana shirya platelets tare da bangon ciki na capillaries don kiyaye mutuncin bangon jijiyoyin jini.Lokacin da jijiyoyin jini suka lalace, ƙaddamarwa ta fara farawa, yana sanya bangon tasoshin jini a cikin ɓangaren da ya lalace kusa da juna, yana raguwa da rauni kuma yana rage gudu.A lokaci guda, platelets suna mannewa, tarawa da sakin abubuwan da ke ciki a sashin da ya lalace, suna kafa thrombus na gida, suna toshe rauni.Hemostasis na jini da platelets ana kiransa hemostasis na farko, kuma tsarin samar da ɗigon fibrin a wurin da aka ji rauni bayan kunna tsarin coagulation don toshe raunin ana kiransa tsarin hemostatic na biyu.

Musamman, coagulation na jini yana nufin tsarin da jini ke canzawa daga yanayin da ke gudana zuwa yanayin gel maras gudana.Coagulation yana nufin cewa jerin abubuwan coagulation suna aiki da sauri ta hanyar enzymolysis, kuma a ƙarshe an samar da thrombin don samar da ƙwayar fibrin.Tsarin coagulation yakan haɗa da hanyoyi guda uku, hanyar coagulation endogenous coagulation, exogenous coagulation path and common coagulation path.

1) Hanyar coagulation na endogenous yana farawa ta hanyar coagulation factor XII ta hanyar amsawar lamba.Ta hanyar kunnawa da amsa nau'ikan abubuwan coagulation iri-iri, a ƙarshe an canza prothrombin zuwa thrombin.Thrombin yana canza fibrinogen zuwa fibrin don cimma manufar coagulation jini.

2) Hanyar coagulation exogenous tana nufin sakin nau'in nama nasa, wanda ke buƙatar ɗan gajeren lokaci don coagulation da saurin amsawa.

Nazarin ya nuna cewa hanyar coagulation na endogenous da kuma hanyar coagulation na waje ana iya kunna juna tare da kunna juna.

3) Hanyar coagulation na gama gari tana nufin matakin coagulation na gama gari na tsarin coagulation na endogenous da tsarin coagulation na waje, wanda galibi ya ƙunshi matakai biyu na haɓakar thrombin da samuwar fibrin.

Abin da ake kira hemostasis da lalacewar jini, wanda ke kunna hanyar coagulation exogenous.Ayyukan physiological na hanyar coagulation endogenous a halin yanzu ba a bayyana sosai ba.Sai dai kuma ya tabbata cewa hanyar da ke tattare da hada jini za a iya kunna ta ne a lokacin da jikin dan Adam ya hadu da kayan aikin wucin gadi, wanda hakan ke nuna cewa kwayoyin halittu na iya haifar da taurin jini a jikin dan Adam, kuma wannan lamarin ya zama wani babban cikas ga aikin. dasa na'urorin likitanci a jikin mutum.

Rashin daidaituwa ko cikas a cikin kowane nau'in coagulation ko haɗin gwiwa a cikin tsarin coagulation zai haifar da rashin daidaituwa ko rashin aiki a cikin tsarin aikin coagulation gaba ɗaya.Ana iya ganin cewa coagulation jini wani tsari ne mai rikitarwa kuma mai laushi a cikin jikin mutum, wanda ke taka muhimmiyar rawa wajen kiyaye rayuwarmu.