1. Plasma D-dimer assay shine gwaji don fahimtar aikin fibrinolytic na biyu.
Ka'idar dubawa: Anti-DD monoclonal antibody an lullube shi akan barbashi na latex.Idan akwai D-dimer a cikin plasma mai karɓa, maganin antigen-antibody zai faru, kuma ƙwayoyin latex zasu tara.Duk da haka, wannan gwajin na iya zama tabbatacce ga duk wani zubar jini tare da samuwar jini, don haka yana da ƙananan ƙayyadaddun ƙayyadaddun bayanai da babban hankali.
2. Akwai tushe guda biyu na D-dimer a vivo
(1) Hypercoagulable jihar da sakandare hyperfibrinolysis;
(2) thrombolysis;
D-dimer yafi nuna aikin fibrinolytic.Ƙara ko tabbatacce da aka gani a cikin hyperfibrinolysis na biyu, irin su hypercoagulable jihar, watsawar intravascular coagulation, renal cuta, ƙin dasawa gabobin, thrombolytic far, da dai sauransu.
3. Muddin akwai thrombosis mai aiki da aikin fibrinolytic a cikin tasoshin jini na jiki, D-dimer zai karu.
Misali: ciwon zuciya na zuciya, ciwon kwakwalwa, ciwon huhu, jijiyar jini, tiyata, ciwon daji, yaduwar jini a cikin jini, kamuwa da cuta da necrosis na nama na iya haifar da karuwar D-dimer.Musamman ga tsofaffi da marasa lafiya a asibiti, saboda ƙwayoyin cuta da sauran cututtuka, yana da sauƙi don haifar da rashin daidaituwa na jini da kuma haifar da karuwar D-dimer.
4. Ƙayyadaddun da aka nuna ta D-dimer ba ya nufin yin aiki a cikin wani takamaiman cuta, amma ga halaye na yau da kullum na wannan babban rukuni na cututtuka tare da coagulation da fibrinolysis.
A ka'ida, samuwar fibrin mai haɗin gwiwa shine thrombosis.Duk da haka, akwai cututtuka da yawa na asibiti waɗanda zasu iya kunna tsarin coagulation a lokacin faruwa da ci gaban cutar.Lokacin da aka samar da fibrin mai haɗin giciye, za a kunna tsarin fibrinolytic kuma za a shafe fibrin mai haɗin gwiwa da ruwa don hana babban "taruwa".(mahimmancin thrombus na asibiti), wanda ya haifar da haɓakar D-dimer sosai.Saboda haka, haɓakar D-dimer ba lallai ba ne ya zama babban thrombosis na asibiti.Ga wasu cututtuka ko daidaikun mutane, yana iya zama tsarin cututtukan cututtuka.